Iron Knuckle appears as the boss of Tykogi Tower in Zelda: The Wand of Gamelon.
Based on the Iron Knuckle of The Adventure of Link, he guards Mayor Kravindish's prison chamber. He shouts that since Zelda walked past him, she defied him and must die. It has been noted his voice and appearance are uncannily similar to Militron. He is struck down using the Power Glove, breaking apart to reveal a Heart Container. Two Armos arrive and quickly decide to leave before Zelda kills them, too.
Iron Knuckle returns in the Quest for YouTube playing the same role.
He returns in numerous Mutant Rampage Bodyslam tournaments.